Best Canker Sore Treatment Products

Canker sores, also called aphthous ulcers, could be very unpleasant, painful and may require a long time treatment.

The exact cause of the appearance of canker sores is still unknown. Most probably, they are the result of an immune system disorder. Emotional stress, menstruation, and mouth trauma often trigger their development.

The small canker sores recover for about a 10 days without leaving a scar. Larger ones heal for a longer period and can leave you with a scar.

They often disappear on their own, although you can influence the healing process by some Over-The-Counter treatments.

The small ulcers that appear on the inside of the lips, mouth, oral cavity, as well as the tongue, can be effectively treated with various remedies, some of which are listed below.

The list below shows the most popular products for canker sores healing (including all the negative effects they may provoke):


Cold Sore Gel

Zilactin Cold Sore Gel, Medicated Gel 0.25 oz
188 Reviews
Zilactin Cold Sore Gel, Medicated Gel 0.25 oz
  • Patented Bio adhesive Promotes Healing
  • Relieves pain for up to 6 hours
  • Cold Sore, Fever Blister, Oral Pain Treatment

Zilactin is an OTC drug, which dries out the canker sore while also putting a protective film over the affected area. More than 80% of the customers find the formula very effective. The product’s active ingredient is 10% Benzyl Alcohol [1] ( a local anesthetic). Below is a very useful advice a customer share:

” This product is best used at the FIRST tingle, warm spot, or if you think it could just be a bump”

Note that it may sting for a minute or so after the application of the product. After that, the substance quickly dries out and you should also have in mind that if you stretch your mouth, move around a lot, it will turn white and flake.

Customer reviews also say that within 2-3 day the canker sore will have completely disappeared, which is very well received since normally the pain, provoked by the ulcer goes away in 7 to 10 days and it can take 1 to 3 weeks for a canker sore to completely heal.


Liquid Antiseptic Oral Cleanser, 2-Ounce Packages

Gly-Oxide Liquid Antiseptic Oral Cleanser, 2-Ounce Packages (Pack of 2)
73 Reviews
Gly-Oxide Liquid Antiseptic Oral Cleanser, 2-Ounce Packages (Pack of 2)
  • For temporary use in cleansing canker sores, minor wounds, gum inflammation, or other irritations
  • Helps guard against the risk of infections in the mouth and gums
  • May be used routinely to improve oral hygiene as an aid to regular brushing

The active ingredient in this product is carbamide peroxide, which is used to help relieve canker sores or other irritations inside the mouth because of its’ strong antibacterial properties.

The product has excellent reviews, reporting that it helps heal mouth ulcers, as it works wonders for any sort of oral infection, according to the customer comments.

People are also satisfied with the price of the product, as they get a pack of 2 oral cleansers. What is really impressive about this product is the absolute lack of negative reviews. What is more, the good reputation of this product is preserved for years.


16 Oz Safe & Effective Herbal Zinc-Plus All Natural Mouthwash – Gluten Free & Vegan, Vitamyr Mouthwash has No SLS, No Sugar, No Fluoride, No Alcohol, No Saccharin, Soothing

VITA-MYR Zinc-Plus Xtra Herbal Mouthwash (16 Oz)
69 Reviews
VITA-MYR Zinc-Plus Xtra Herbal Mouthwash (16 Oz)
  • VITA-MYR Natural Products! Only Natural Ingredients! Zinc, Folic Acid, Clove, Myrrh Oil, Distilled...
  • Simply gargle with Vita-Myr Mouthwash for great cleansing action & fresh breath!!
  • Enjoy the benefits of the natural ingredients, Myrrh & Clove oil, used traditionally through the...

The full list of containing ingredients includes Zinc, Folic Acid, Clove, Myrrh, Distilled Water. Zinc may help mouth injuries like canker sores heal faster; folic acid promotes cell reproduction; clove will help numb the pain; and myrrh is often used as a mouthwash to treat various types of mouth and gum ailments, including sore gums, bad breath, and canker sores treatment.

Unfortunately, there are very few reviews about the product but the good news is that the published ones are very positive. The mouthwash has no chemical colors, no preservatives, no additives.

It can even be used every day, as it has no negative effect on the mouth cavity and keeps the teeth and gums healthy. After purchasing the product, you should simply gargle Vita-Myr Natural Mouthwash for great cleansing action and fresh breath.


Natural Canker Sore Relief, Healing & Prevention: (Lysine, B12, ProBiotics & more!) Eat again. Drink again. Smile again! 15 – 6.1 g packets/ net Wt 3.2 oz (91.5g)

CankerYanker® Natural Canker Sore Relief, Healing & Prevention: (Lysine,...
103 Reviews
CankerYanker® Natural Canker Sore Relief, Healing & Prevention: (Lysine,...
  • CankerYanker is now SENSAJOY - Fight canker sores & promote oral health: √ ProBiotics √ Vitamins...
  • SOOTHING RELIEF: Go about your day without oral discomfort (Vitamin E, ProBiotics, L-Lysine)
  • QUICKER HEALING: Replenish deficiencies that trigger mouth ulcers (B12, zinc, selenium, folate)

The product is a nutritional dietary supplement. It contains multiple vitamins, amino acids, and loads of other ingredients promoting the healing process. What you should do is our pour one packet into 6-8 fl. oz. of cold water and mix well, then wait until the effervescence ceases before drinking (1 pack contains 10 calories).

There are lots of reviews about this product but, unfortunately, its’ rating is not impressive at all. Here’s a review, which summarizes the real purpose of the product:

“This product just provides a quick boost in the case of a canker sore outbreak. By no means a cure, simply a supplement. Helped me slowly clear a few breakouts.”

In general, the product would resolve the problem with canker sores for people with nutritional deficiencies, but there are also loads of negative comments, informing that Canker Yanker has temporary effect only or does not work at all, so apparently it depends on the individual.


Get Immediate Relief and Heal Canker Sores

Canker-Rid® - Get Immediate Relief and Heal Canker Sores - Restore Your...
1084 Reviews
Canker-Rid® - Get Immediate Relief and Heal Canker Sores - Restore Your...
  • Effective canker sore treatment.
  • Immediate relief of pain and healing process
  • Low Cost Next Day Delivery Available

Canker-Rid has almost 1000 reviews, almost 80% of which describes it as an excellent product. The description says that the pain from the sore will stop almost immediately.

The basic ingredient is propolis a naturally-occurring bee product) which is proven to be very effective against mouth ulcers [2].

Customers advise using a Q-tip for the application, as the substance should be applied on the canker sore.

A downside about the product is that it is very strong and may sting:

” I mean your sore doesn’t even have to be popped or anything, this canker-rid is just a damn minty. I personally don’t mind it but it’s just a fair warning.”

Aside from that, customers find the product:

“Truly a life saver!!!”


test allergic reaction behind ear

Everyone's skin is unique, and even if you have chosen the best product for your skin condition, the containing ingredients may still cause some irritation, burning sensation, rash or allergy.

To avoid potential skin reactions, we highly recommend performing a patch test before using the product (you can download printable PDF version here)

Last update on 2018-05-18 / Affiliate links / Images from Amazon Product Advertising API

About the author

Monica H.

Monika is the Editor-in-Chief at SkinPractice. She is a skin care addict and researcher, who feels strongly about helping people with different dermatology conditions from alopecia to warts.

You can read her recommendations and advice both here at SkinPractice or at Quora where she answers skincare-related questions frequently and is the most viewed author in the Skincare category with more than 2 million views.

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